The daily dose for Safe-Guard® Canine is 50 mg/kg (22.7 mg/lb) of body weight. You should weigh your dog to make sure you are using the right dose; i.e. correct gram amount and appropriate number of pouches. Your dog must be treated with the following dose for 3 days in a row. One packet treats a 40 pound dogs. Repeat the dose for 3 days in a row. Mix daily dose with a small amount of the usual food. Make sure your dog eats all the medicated food. You may need to moisten dry dog food to aid mixing.